Dominique Joubert Selected Research

big gastrin

2/2022	hPG80 (Circulating Progastrin), a Novel Blood-Based Biomarker for Detection of Poorly Differentiated Neuroendocrine Carcinoma and Well Differentiated Neuroendocrine Tumors.
10/2021	A novel method to detect hPG80 (human circulating progastrin) in the blood.
1/2021	Prognostic Value of Plasma hPG80 (Circulating Progastrin) in Metastatic Renal Cell Carcinoma.
1/2020	The oncogenic and druggable hPG80 (Progastrin) is overexpressed in multiple cancers and detected in the blood of patients.
9/2017	Targeting the Wnt Pathway and Cancer Stem Cells with Anti-progastrin Humanized Antibodies as a Potential Treatment for K-RAS-Mutated Colorectal Cancer.
1/2016	Autocrine Secretion of Progastrin Promotes the Survival and Self-Renewal of Colon Cancer Stem-like Cells.
8/2009	The wnt target jagged-1 mediates the activation of notch signaling by progastrin in human colorectal cancer cells.
11/2007	Beta-catenin/Tcf-4 inhibition after progastrin targeting reduces growth and drives differentiation of intestinal tumors.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Dominique Joubert Research Topics

Disease

14	Neoplasms (Cancer) 02/2022 - 01/2005
8	Colorectal Neoplasms (Colorectal Cancer) 01/2020 - 11/2007
4	Carcinogenesis 02/2012 - 11/2007
2	Colonic Neoplasms (Colon Cancer) 01/2016 - 03/2010
2	Adenoma (Adenomas) 11/2007 - 11/2007
1	Neuroendocrine Tumors (Neuroendocrine Tumor) 02/2022
1	Neuroendocrine Carcinoma 02/2022
1	Infections 01/2022
1	Renal Cell Carcinoma (Grawitz Tumor) 01/2021
1	Lung Neoplasms (Lung Cancer) 01/2020
1	Hepatocellular Carcinoma (Hepatoma) 09/2014
1	Liver Cell Adenoma (Hepatocellular Adenoma) 09/2014
1	Glioblastoma (Glioblastoma Multiforme) 02/2013
1	Squamous Cell Carcinoma of Head and Neck 08/2009
1	Hyperplasia 11/2007
1	Adenomatous Polyposis Coli (Familial Adenomatous Polyposis) 11/2007
1	Carcinoma (Carcinomatosis) 02/2007
1	Urinary Bladder Neoplasms (Bladder Cancer) 02/2007
1	Alzheimer Disease (Alzheimer's Disease) 03/2003
1	Pituitary Neoplasms (Pituitary Adenoma) 12/2002

Drug/Important Bio-Agent (IBA)

8	big gastrinIBA 02/2022 - 11/2007
3	Peptides (Polypeptides)IBA 01/2021 - 01/2016
3	Small Interfering RNA (siRNA)IBA 02/2012 - 11/2007
2	Biomarkers (Surrogate Marker)IBA 02/2022 - 02/2010
2	Messenger RNA (mRNA)IBA 01/2020 - 03/2010
2	CateninsIBA 09/2017 - 02/2012
2	Protein Kinase CIBA 07/2009 - 01/2005
2	Protein Isoforms (Isoforms)IBA 02/2007 - 01/2005
1	Indicators and Reagents (Reagents)IBA 01/2022
1	Pharmaceutical PreparationsIBA 01/2020
1	Tumor Suppressor Proteins (Proteins, Tumor Suppressor)IBA 01/2018
1	Humanized Monoclonal AntibodiesIBA 09/2017
1	LuciferasesIBA 09/2014
1	Transcription Factors (Transcription Factor)IBA 02/2013
1	ArrestinsIBA 02/2012
1	Food Additives (Food Additive)IBA 03/2010
1	Pregnane X ReceptorIBA 03/2010
1	Topoisomerase I InhibitorsIBA 03/2010
1	Irinotecan (Camptosar)FDA LinkGeneric 03/2010
1	Claudin-2IBA 02/2010
1	tributyl phosphate (TBP)IBA 08/2009
1	Hypoxanthine Phosphoribosyltransferase (Hypoxanthine Guanine Phosphoribosyltransferase)IBA 08/2009
1	Jagged-1 ProteinIBA 08/2009
1	1-phenyl-3,3-dimethyltriazene (PDT)IBA 07/2009
1	rat Ybx3 proteinIBA 11/2007
1	GastrinsIBA 11/2007
1	beta CateninIBA 11/2007
1	Glycine (Aminoacetic Acid)FDA LinkGeneric 11/2007
1	Ethanol (Ethyl Alcohol)IBA 11/2007
1	phosphatidylethanolIBA 11/2007
1	TransferasesIBA 02/2007
1	Claudin-4IBA 02/2007
1	ClaudinsIBA 02/2007
1	Proteins (Proteins, Gene)FDA Link 02/2007
1	Green Fluorescent ProteinsIBA 01/2005
1	Carrier Proteins (Binding Protein)IBA 03/2003
1	Caspase 3 (Caspase-3)IBA 12/2002
1	CaspasesIBA 12/2002
1	CalpainIBA 12/2002

Therapy/Procedure

3	Therapeutics 01/2020 - 11/2007
2	Drug Therapy (Chemotherapy) 09/2017 - 03/2010